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I buy these things but I wonder if they are truly pharmacologically-active and not just bullshit. Discuss

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[-] squiblet@kbin.social 52 points 1 year ago* (last edited 1 year ago)

The aromatic oils in plants contain the same sorts of chemicals like terpenes as in cannabis, and many are known to be pharmacologically active, including mental effects. Myrcene, for instance, is abundant in most cannabis and also found in verbena, lemon grass, hops, mango, West Indian bay tree, and cardamom.

For example here's a paper about the psychological effects of mint oil: Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil

Another one...
Therapeutic and Medicinal Uses of Terpenes

[-] Very_Bad_Janet@kbin.social 7 points 1 year ago

Spearmint tea is also beneficial for acne.

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[-] 01189998819991197253@infosec.pub 3 points 11 months ago

Ever had black coffee with cardamom? It's very tasty, imo, and it has a strange calming effect on me, despite having a bunch of caffeine. Almost like the world just quieted, allowing me to hear everything more clearly. I've never known why, but maybe this is a reason.

[-] Thavron@lemmy.ca 33 points 11 months ago

As Tim Minchin said:

Do you know what they call alternative medicine that's been proven to work?

Medicine.

[-] Snejp@feddit.uk 14 points 11 months ago

Water has memory and whilst its memory of a long lost drop of onion juice seems infinite, it somehow forgets all the poo it's had in it.

[-] Seasm0ke@lemmy.world 7 points 11 months ago

I mean, a natural medicine doesn't cease to exist after a pharmacologist "discovers" its use. Willow tree bark is used to make asprin but there are still warnings out there that there is no scientific proof of its efficacy.

Maybe the medicine derived from salicylic acid is the only effective thing about it, or maybe other presently unknown compounds contribute in a way that will later be used to develop a new medicine.

Valerian root for example has been proven in animal studies and other clinical trial to have some effects, and possibly interact with GABA receptors but the mechanism is unknown and it is still described as having no science to back up its uses, despite being similar to Willow in history.

I'm not saying this to encourage people who go 100% naturopathic and might swear that all modern medicine is a poison. Just want to include some nuance in a conversation thats is often way too extreme in its convictions either way.

Further reading

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[-] DogMuffins@discuss.tchncs.de 24 points 11 months ago

Not bullshit but not magic either.

For example, L-Theanine is psychoactive, lots of clinical support for that.

Additionally, I would say that the ritual around "sitting down and having a nice relaxing cup of lemon & ginger tea" has some calming benefits in itself - even if those benefits are not from the ingredients in the tea.

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[-] room_raccoon@kbin.social 24 points 1 year ago

Whatever the heck lemongrass actually does, it sure tastes delicious

[-] cheese_greater@lemmy.world 12 points 1 year ago

It never seems to get its own one-man show, its always lumped with at least like 5 other ingredients so I can't isolate it but I'm sure you're correct. I love lemon + I love grass so ya

[-] room_raccoon@kbin.social 19 points 1 year ago

I think the taste can be somewhat prominent in Thai curries and soups at least

[-] squiblet@kbin.social 4 points 1 year ago

It’s so good in that context! I grew some last year but uh…. never ate it. Didn’t get that large though.

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[-] Doug@midwest.social 23 points 1 year ago

A worthwhile thing to keep in mind whether it's for tea, supplements, or whatever, is that medication is based on things that were observed from "natural" sources.

For example, willow bark was/is/has been used for pain and inflammation. It also contains salicin which is similar to acetysalicylic acid, which you'll know better as aspirin.

Does that mean all the things people say do a thing work? Not at all. Do some of them have varying degrees of effect of some percentage of people? Yes.

[-] jmp242@sopuli.xyz 22 points 1 year ago

Like all of the supplement industry, it will depend on a couple things. One, what are the regulations in your country? How well are they enforced?

In the US, there is next to no regulation or enforcement, so often these things don't contain what they claim to, or not the amount claimed. So you're looking at third party testing groups or just trusting the manufacturer. Mostly the adulteration isn't harmful, but generally inert. So if there's very little or nothing there, it's most likely placebo.

Next - even if you do get the dose of what it claims - I think it's still very likely placebo, extremely weak or extremely variable effect. "alternative medicine" that has consistent effects on most people every time even when they don't know what they're taking isn't usually alternative anymore - we just call it medicine.

All that said - I personally don't see any issue with using a placebo for psychological issues - "it's all in my head" so applying a "just in my head" fix seems reasonable as long as it's working for me.

[-] cheese_greater@lemmy.world 20 points 1 year ago

In case I'm perceived as biased or part of BigAntiCalmingTea, I'm consuming a cup right now...

[-] bestnerd@lemmy.world 11 points 1 year ago

Have you tried the enema method?

[-] cheese_greater@lemmy.world 15 points 1 year ago* (last edited 11 months ago)

No comment (;) [butthole wink]

[-] room_raccoon@kbin.social 6 points 1 year ago

Are you a the Snow Plow Show fan or are butthole winks from something else I don't know about?

[-] cheese_greater@lemmy.world 4 points 1 year ago* (last edited 1 year ago)

I have no idea. I was just riffing ;)

[-] Synnr@sopuli.xyz 5 points 1 year ago

Riffing. There's a word used far too little, I hope I remember it later so I can use it later. 'joking around', 'kidding' 'just joshing'... I need more riffing in my life.

[-] cheese_greater@lemmy.world 3 points 11 months ago

See Robin Williams

[-] Ransom@lemmy.one 5 points 1 year ago

My b-hole winked when I read this.

[-] givesomefucks@lemmy.world 8 points 1 year ago

Everyone's biochemistry is different, that's why we had the opioid epidemic and not an opioid pandemic...

It might work on others, but not you. And for a decent amount of people it works for, a significant amount are having the placebo effect.

So just go into it with an open mind thinking it may relax you, and it might. Even though I've just told you it could be placebo, that doesn't hurt it's chances. (Crazy side note: the opposite of a placebo is a nocebo, something that gives a negative effect. Being aware of that does prevent it).

If you do it for a while, simply the act of putting a kettle on would have you relaxed before you've taken a drink. It doesn't matter why it works, just that it does.

[-] Synnr@sopuli.xyz 3 points 1 year ago* (last edited 1 year ago)

that's why we had the opioid epidemic and not an opioid pandemic...

Maybe. But I think there are also just a lot of people that are not dealing with enough trauma and mental pain (pain-killers/type not specific) that their inner voice stops them from seeking it out.

My dad had a friend with brain cancer. He was in hospice many years ago and knew that I had struggled with addiction. He said he had received hydrocodone and oxycodone after surgeries before (he'd had many) but they always made him nauseous and feel like shit. Then at the end when he was in hospice they gave him a fentanyl patch. He said "MyName, WOW, I FINALLY UNDERSTAND how people can get addicted to this stuff now. This is remarkable!"

Off-topic story: shortly after he passed I was looking for ways to painlessly "catch the bus" on the internet (I'm fine now, this was many moons ago) and bawling my eyes out as I thought about my family and what I'd be putting them through. Suddenly, the piano next to me blasted as if someone had pounded 10 of the keys at once as hard as they possibly could. No pets, no other people home.

I've been through a lot since then and am happy to say I am doing fine now, but that's one of those many WTF moments that turned me from a staunch materialistic atheist into a more spiritually understanding person.

That and the DMT. Only slightly riffing, DMT came way before that.

[-] cheese_greater@lemmy.world 3 points 11 months ago

There's a convention or interpolation wirh regard to opioids/opiates such that:

  1. 1/3 hate it (side effects)
  2. 1/3 are neutral (it attenuates their physical pain and nothing else
  3. 1/3 LOVE. IT. (euphoria, complacency, acceptance of otherwise intolerable contexts)
[-] givesomefucks@lemmy.world 2 points 1 year ago

Well, yeah...

Your first example needs metabolized into an active ingredient. The second is an active ingredient.

There's a bunch of different liver enzymes at play, and an absolute shit ton of normal variation between people.

Too much of those enzymes, and you burn through a 12 hr oxy in 6 hours, which makes people likely to abuse their own medication and can lead to life long addicts.

Too little and you get zero effect from "normal" opioids, but fentanyl, morphine, and other direct action opioids stick around for a lot longer and you have no tolerance.

That's what I'm saying:

Everyone’s biochemistry is different,

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[-] cheese_greater@lemmy.world 6 points 1 year ago

Not gonna lie, I'm kinda tempted to start a line of rage-inducing Anti-Calming teas...Maybe ephedra or some shit

[-] Mothra@mander.xyz 12 points 1 year ago

Lots of comments talking about product quality and research, and that's totally true. However bear in mind that when it comes to infusions, the effects are likely to always be mild, and you also have a lot of personal taste influencing your reaction.

Take for example camomile, which has anti inflammatory properties. But how much camomile are you consuming with a single cup of camomile"tea"? Not much; also, the effects are topical ( on contact), and a drink usually doesn't stay for too long on the same spot of your throat. A cup of camomile isn't going to make a massive difference if you have inflammation on a tooth gum or your throat, and it won't do anything for inflammation on your knee. And if you dislike the smell and taste, that's not going to help at all.

[-] Moghul@lemmy.world 10 points 1 year ago

I just googled it and it says this:

Amino acids and fragrance substances in tea can calm us down. In late night, a calming tea can help us sleep better. Theanine's calming effect is the long-term result of tea-drinking. The higher theanine content can effectively suppress caffeine's stimulation in our nerve system.

[-] cheese_greater@lemmy.world 8 points 1 year ago* (last edited 1 year ago)

I think theanine has the best claim to this

Edit: Sometimes I wonder if its legit more aromatherapy than pharmacotherapy. Ain't hating on it, whatever fucking works :)

Whatever keeps the wolves from the door(s of consciousness)

[-] MxM111@kbin.social 9 points 1 year ago
[-] Enkers@sh.itjust.works 3 points 1 year ago

Not only is it real, but you can still benefit from placebos knowing that they're placebos! VSauce did a pretty cool episode on it: https://youtube.com/watch?v=QDCcuCHOIyY

[-] PipedLinkBot@feddit.rocks 3 points 1 year ago

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[-] GuyFi@lemmy.sdf.org 8 points 1 year ago

Maybe it is, but that shit really helps me

[-] Candelestine@lemmy.world 6 points 1 year ago

A lot of them are just subjectively calming your mind, I think, by being warm, soothing and pleasant. The main exception for me is chamomile, which I have seen some minor results with. Which is slightly annoying because I don't particularly like the flavor. At all.

It doesn't help me stay asleep though, just fall asleep. Can work sometimes when I've had a little too much caffeine.

[-] Synnr@sopuli.xyz 3 points 1 year ago

Melatonin helps me stay and fall asleep, which is bad for me somewhat considering I can easily accidentally sleep 12 hours if my alarm goes off during a deep sleep cycle. But if I had something to help me fall asleep and maybe calm me for a few hours, that'd be ideal.

Maybe I'll try some chamomile.

[-] Synnr@sopuli.xyz 5 points 1 year ago

It depends completely on the plant, the processing (if any), and other factors. I know nothing about lemongrass but St Johns Wort for example is GABAergic, acts on serotonin and dopamine, and under controlled trials shows clinical significance.

Placebo is one of those factors and it can be a MASSIVE factor. Conversely, nocebo, the opposite of placebo shows that if patients do not believe something will work, even though it's shown highly significant clinical success, chances of it working on them are far less.

[-] FluffyPotato@lemm.ee 5 points 1 year ago

I haven't noticed lemongrass calming me but I like the flavour though I'm generally pretty calm already.

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[-] 01189998819991197253@infosec.pub 4 points 11 months ago

Are you talking about specifically tea, or are you talking about tisanes, in general?

[-] thelastknowngod@lemm.ee 4 points 11 months ago

I remember going to a tea shop years ago. The person working there asked if I wanted one of the samples they had. The conversation went like this:

"It's good for heart health, your liver, and getting rid of toxins."

"Does it taste good too?"

"Oh yeah. Of course."

"Ok. Let's start there."

Tea can do many things but it's not medicine. That's stupid.

[-] riley0@lemmy.dbzer0.com 4 points 1 year ago

Some work; some don't. Google Scholar is a good way to find out whether testing's been done. Here are 2 less time-consuming ways 1) https://ods.od.nih.gov/factsheets/list-all/ 2) https://examine.com/ The other thing to watch out for is whether the bottle you're buying actually contains what it says it does. The only verifying organizations I know of are NSF and USP. Manufacturers have to pay for those lab tests, and if they do, they post NSF or USP logos on the bottles. If you just look for "natural" or "organic," you won't find anything about the presence or absence of the supposedly active ingredient. As jmp242 said, there's no regulation in the USA, so there's a lot of snake oil.

[-] glomag@kbin.social 2 points 1 year ago* (last edited 1 year ago)

Good points, I just wanted to mention another database that is useful for finding information about supplements based on actual research studies. Unfortunately it requires a subscription but some Universities and Libraries can provide access.

https://naturalmedicines.therapeuticresearch.com/

[-] CarlCook@feddit.de 4 points 1 year ago

By personal (yet anecdotal) evidence, I can testify that at least camomile works. The regular tea is not concentrated enough for me to have any noticeable effect, but the oily extract (apigenin) does wonders for my stressed-out brain!

[-] fred@lemmy.ml 2 points 1 year ago

Give skullcap a try if you can find the extract or a tea, that one worked super well for me to help get to sleep

[-] cheese_greater@lemmy.world 2 points 1 year ago

What do you think or Yogi-brand teas?

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this post was submitted on 25 Sep 2023
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