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Jeff Geerling: "Raspberry Pi 5: Everything you need to know"
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Whata wrong with running retro games on LCD? The only issue I can see is games that use a light gun.
You'll get at least one frame of added latency in the very best case when using original hardware on an LCD. Combine that with a TV that does its own processing and emulation and you'll have some noticeable input lag. And yes, I know most TVs have a game mode.
Interlacing when doing sprite multiplexing looks shittier on an LCD, too. Unless you do blending at the cost of an additional frame of latency.