Debatable whether there is a disincentive, the conventional wisdom as to how it came about was that toys are marketed in a gendered way and Nintendo decided to explicitly target their products at boys only to avoid spending double on ads.

If they were right, and marketing costs were not commensurate then, we might have passed the break even point since, but that's no guarantee.

Plus it's objectively easier to make successful products for a narrower audience (though "men" isn't exactly narrow).