It depends what "From Scratch" means to you, as I don't know your level of programming or interests, because you could be talking about making a game from beginning to end, and you could be talking about...

• Using a general purpose game engine (Unity, Godot, Unreal) and pre-made assets (e.g., Unity Asset Store, Epic Marketplace)?
• Using a general purpose game engine almost purely as a rendering+input engine with a nice user interface and building your own engine overtop of that
• Using frameworks for user input and rendering images, but not necessarily ones built for games, so they're more general purpose and you'll need to write a lot of game code to put it all together into your own engine before you even starting "Making the game", but offer extreme control over every piece so that you can make something very strange and experimental, but lots of technical overhead before you get started
• Writing your own frameworks for handling user input and rendering images... that same as previous, but you'll spend 99% of your time trying to rewrite the wheel and get it to go as fast as any off the shelf replacement

If you're new to programming and just want to make a game, consider Godot with GDScript - here's a guide created in Godot to learn GDScript interactively with no programming experience. GDScript is like Python, a very widely used language outside of games, but it is exclusive to Godot so you'll need to transfer it. You can also use C# in Godot, but it's a bigger learning curve, though it is very general and used in a lot of games.

I'm a big Godot fan, but Unity and Unreal Engine are solid. Unreal might have a steeper learning curve, Godot is a free and open-source project with a nice community but it doesn't have the extensive userbase and forum repository of Unity and Unreal, Unity is so widely used there's lots of info out there.

If you did want to go really from scratch, you can try using something like Pygame in Python or Processing in Java, which are entirely code-created (no user interface) but offer lots of helpful functionality for making games purely from code. Very flexible. That said, they'll often run slow, they'll take more time to get started on a project, and you'll very quickly hit a ceiling for how much you can realistically do in them before anything practical.

If you want to go a bit lower, C++ with SDL2, learning OpenGL, and learning about how games are rendered and all that is great - it will be fast, and you'll learn the skills to modify Godot, Unreal, etc. to do anything you'd like, but similar caveats to previous; there's likely a low ceiling for the quality you'll be able to put out and high overhead to get started on a project.